4-methyl-5-(2-piperazin-1-ylethyl)-2-benzofuran-1(3H)-one hydrochloride → 4-Methyl-5-[2-[4-[2-[6-(tetrazol-1-yl)-3-pyridyl)ethyl]piperazin-1-yl]ethyl]-3H-isobenzofuran-1-one

Participants

Reaction Steps

4-Methyl-5-[2-[4-[2-[6-(tetrazol-1-yl)-3-pyridyl]ethyl]piperazin-1-yl]ethyl]-3H-isobenzofuran-1-one was prepared in a similar fashion to that described for the synthesis of Example 38 starting from 4-methyl-5-[2-(piperazin-1-yl)ethyl]-2-benzofuran-1(3H)-one hydrochloride and [6-(1H-tetrazol-1-yl)pyridin-3-yl]acetaldehyde. LC-MS (IE, m/z): 406.1 [(M+1)+−28]. (0.61 μm)

Provenance & Evidence