HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-4-methylthiophene-3-carboxamide → 4-Methyl-2-(2-(2-oxo-3,4-dihydroquinolin-1(2H)-yl)acetamido)thiophene-3-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-4-methylthiophene-3-carboxamide | HCID 293810 | — |
| Reactant | 2-(2-Oxo-1,2,3,4-tetrahydroquinolin-1-yl)acetic acid | HCID 16784221 | — |
| Product | 4-Methyl-2-(2-(2-oxo-3,4-dihydroquinolin-1(2H)-yl)acetamido)thiophene-3-carboxamide | HCID 68755949 | — |
Reaction Steps
4-Methyl-2-(2-(2-oxo-3,4-dihydroquinolin-1(2H)-yl)acetamido)thiophene-3-carboxamide was prepared from 2-(2-oxo-3,4-dihydroquinolin-1(2H)-yl)acetic acid (0.49 g, 2.38 mmol) and 2-amino-4-methylthiophene-3-carboxamide (0.37 g, 2.38 mmol) according to protocol B Retention time (min)=3.405, method [1], MS(ESI) 344.0 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09073891B2 |
| Source dataset | uspto-grants-2015_07 |
| ORD ID | ord-ce50070482ca416b89fbd0721561f643 |
| Source note | uspto-grants-2015_07 |