HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 2-amino-4-methylthiophene-3-carboxylate → Methyl 4-methyl-2-(2-(2-oxo-3,4-dihydroquinolin-1(2H)-yl)acetamido)thiophene-3-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 2-amino-4-methylthiophene-3-carboxylate | HCID 2759773 | — |
| Reactant | 2-(2-Oxo-1,2,3,4-tetrahydroquinolin-1-yl)acetic acid | HCID 16784221 | — |
| Product | Methyl 4-methyl-2-(2-(2-oxo-3,4-dihydroquinolin-1(2H)-yl)acetamido)thiophene-3-carboxylate | HCID 53322984 | — |
Reaction Steps
The title compound was prepared from 2-(2-oxo-3,4-dihydroquinolin-1(2H)-yl)acetic acid (0.43 g, 2.09 mmol) and methyl 2-amino-4-methylthiophene-3-carboxylate (0.358 g, 2.09 mmol) according to protocol B. Retention time (min)=6.895, method [7], MS(ESI) 359.1 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09073891B2 |
| Source dataset | uspto-grants-2015_07 |
| ORD ID | ord-79d318e794014cc8b043ab5f3fa610ba |
| Source note | uspto-grants-2015_07 |