2-Amino-4-methylthiophene-3-carboxamide → 4-Methyl-2-(2-(quinoxalin-5-yl)acetamido)thiophene-3-carboxamide

HRID 1519774Notes

Reaction equation

HRID 1519774 reaction equation
[N:1]1[C:10]2[C:5](=[C:6]([CH2:11][C:12]([OH:14])=O)[CH:7]=[CH:8][CH:9]=2)[N:4]=[CH:3][CH:2]=1.[NH2:15][C:16]1[S:17][CH:18]=[C:19]([CH3:24])[C:20]=1[C:21]([NH2:23])=[O:22]>>[CH3:24][C:19]1[C:20]([C:21]([NH2:23])=[O:22])=[C:16]([NH:15][C:12](=[O:14])[CH2:11][C:6]2[CH:7]=[CH:8][CH:9]=[C:10]3[C:5]=2[N:4]=[CH:3][CH:2]=[N:1]3)[S:17][CH:18]=1

Participants

3

Reactant 2

HCID 2938102-Amino-4-methylthiophene-3-carboxamideHCID 177818242-(Quinoxalin-5-yl)acetic acid

Product 1

HCID 687562074-Methyl-2-(2-(quinoxalin-5-yl)acetamido)thiophene-3-carboxamide

Procedure

The title compound was prepared from 2-(quinoxalin-5-yl)acetic acid and 2-amino-4-methylthiophene-3-carboxamide using protocol B. Method[1], MS(ESI) 327.0 [M+H], Retention time=1.644 min.

Sources & evidence

ORD record
ord-41687d7099ec4a558ee4bfcb736dfbea
Source dataset
uspto-grants-2015_07
Patent number
US09073891B2

Reaction notes

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