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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1519932Generated: November 2, 2026

2-(Thiazol-4-yl)thiophen-3-amine → HCID 68784811, compound

https://huagongshe.com/reaction/1519932

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Thiazol-4-yl)thiophen-3-amineHCID 68755362—
Reactant2-(2-oxo-6-(trifluoromethyl)quinolin-1(2H)-yl)acetic acidHCID 68759857—
ProductHCID 68784811HCID 68784811—

Reaction Steps

The title compound was prepared from 2-(thiazol-4-yl)thiophen-3-amine and 2-(2-oxo-6-(trifluoromethyl)quinolin-1(2H)-yl)acetic acid according to protocol A. Retention time (min)=6.485, method [7], MS(ESI) 436.1 (M+H); 1H NMR (300 MHz, CD3Cl) δ 11.32 (s, 1H), 8.51 (d, J=1.5 Hz, 1H), 8.04 (d, J=5.5 Hz, 1H), 7.92 (d, J=10.2 Hz, 1H), 7.90 (s, 1H), 7.80 (d, J=8.9 Hz, 1H), 7.50 (d, J=8.9 Hz, 1H), 7.22 (d, J=1.4 Hz, 1H), 7.20 (d, J=5.5 Hz, 1H), 7.03 (d, J=9.7 Hz, 1H), 5.23 (s, 2H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09073891B2
Source datasetuspto-grants-2015_07
ORD IDord-d51ea3a1a2f644499c3fde073a30588f
Source noteuspto-grants-2015_07