HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 68756029, compound → HCID 56675421, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 68756029 | HCID 68756029 | — |
| Reactant | 2-(2-oxo-6-(trifluoromethyl)quinolin-1(2H)-yl)acetic acid | HCID 68759857 | — |
| Product | HCID 56675421 | HCID 56675421 | — |
Reaction Steps
The title compound was synthesized from 5-amino-4-(oxazol-2-yl)thiophene-3-carbonitrile (21 mg, 0.11 mmol) and 2-(2-oxo-6-(trifluoromethyl)quinolin-1(2H)-yl)acetic acid (30 mg, 0.11 mmol) according to protocol A. The product was purified by HPLC. LCMS method [7], retention time=6.70 min; MS(ESI) 445.0 (MH+); 1H NMR (300 MHz, CD3OD) δ 8.19 (d, J=9.8 Hz, 2H), 7.95-7.80 (m, 3H), 7.85 (d, J=1.8 Hz, 1H), 7.08 (d, J=0.8 Hz, 1H), 6.90 (d, J=9.6 Hz, 1H), 5.45 (s, 2H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09073891B2 |
| Source dataset | uspto-grants-2015_07 |
| ORD ID | ord-5a79eae0143446f7a47d40451991ff9a |
| Source note | uspto-grants-2015_07 |