Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Methoxyphenylacetic Acid → 2-(4-Methoxyphenyl)-N-(2-(pyrazin-2-yl)thiophen-3-yl)acetamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Methoxyphenylacetic Acid | HCID 7690 | — |
| 반응물 | 2-(Pyrazin-2-yl)thiophen-3-amine | HCID 68757596 | — |
| 생성물 | 2-(4-Methoxyphenyl)-N-(2-(pyrazin-2-yl)thiophen-3-yl)acetamide | HCID 52941286 | — |
반응 단계
The title compound was prepared from 2-(pyrazin-2-yl)thiophen-3-amine and 2-(4-methoxyphenyl)acetic acid according to protocol B and was purified by HPLC. Method [7] Retention time 5.91 min by HPLC (MH+ 326). 1H NMR (300 MHz, DMSO) δ s (11.02, 1H), 8.81 (d, J=0.9 Hz, 1H), 8.45 (d, J=2.7 Hz, 1H), 8.26 (m, 1H), 7.92 (d, J=5.4 Hz, 1H), 7.74 (d, J=5.4 Hz, 1H), 7.33 (d, 8.7 Hz, 2H), 6.99 (d, J=8.7 Hz, 2H), 3.78 (s, 3H), 3.72 (s, 2H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09073891B2 |
| 출처 데이터셋 | uspto-grants-2015_07 |
| ORD ID | ord-ef5373f2ef1e4fcea2028002948f5a8e |
| 출처 메모 | uspto-grants-2015_07 |