HCID 18998824, compound → HCID 68194088, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of methyl 3-chloro-2-oxo-1,2-dihydroquinoxaline-6-carboxylate (161 mg, 0.67 mmol) in NMP (5 ml) was added the 2H,5H,6H,7H,8H-[1,3]dioxolo[4,5-g]quinoline (180 mg, 1.02 mmol) and the reaction was stirred for 1 h at 140° C. The reaction mixture was cooled to room temperature, and the product was precipitated by the addition of water and filtered off to afford methyl 3-[2H,5H,6H,7H,8H-[1,3]dioxolo[4,5-g]quinolin-5-yl]-2-oxo-1,2-dihydroquinoxaline-6-carboxylate as a brown solid (140 mg, 55%).

Provenance & Evidence