Methyl 6-aminonicotinate → HCID 117840000, compound

HRID 1520274Notes

Reaction equation

HRID 1520274 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8](Cl)[CH:9]2[CH2:14][CH2:13][CH2:12][CH2:11][CH2:10]2)=[C:4]([CH3:16])[CH:3]=1.[NH2:17][C:18]1[CH:27]=[CH:26][C:21]([C:22]([O:24][CH3:25])=[O:23])=[CH:20][N:19]=1>>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([NH:17][C:18]2[CH:27]=[CH:26][C:21]([C:22]([O:24][CH3:25])=[O:23])=[CH:20][N:19]=2)[CH:9]2[CH2:14][CH2:13][CH2:12][CH2:11][CH2:10]2)=[C:4]([CH3:16])[CH:3]=1

Participants

3

Reactant 2

HCID 737487Methyl 6-aminonicotinateHCID 117841023HCID 117841023, compound

Product 1

HCID 117840000HCID 117840000, compound

Procedure

Using 4-bromo-1-(chloro(cyclohexyl)methyl)-2-methylbenzene obtained in Example 16, step B and methyl 6-aminonicotinate, and in the same manner as in Example 1, step D, the title compound was obtained.

Sources & evidence

ORD record
ord-43cb9fa2be4c430883bf926a3861288d
Source dataset
uspto-grants-2015_07
Patent number
US09073864B2

Reaction notes

Loading…