HRID1520946

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID14760311

未命名化合物

结构：CCCC(Nc1ccc(-n2cc(-c3ccccc3)cn2)nc1)c1ccc(C(=O)OCC)cc1

HCID68157145

未命名化合物

PRODUCTS

生成物

结构：CCCC(Nc1ccc(-n2cc(-c3ccccc3)cn2)nc1)c1ccc(C(=O)N(C)CCC(=O)OC(C)(C)C)cc1

HCID68178655

未命名化合物

PROCEDURE

实验过程

The title compound was prepared by a method analogous to that described in Steps B and C of Example 2, using ethyl 4-(1-(6-(4-phenyl-1H-pyrazol-1-yl)pyridin-3-ylamino)butyl)benzoate and tert-butyl 3-(methylamino)propanoate. MS (M+1) 554.5.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-ac57c865ef664391be0b7600bca1b579
来源数据集: uspto-grants-2015_07
DOI: 10.6084/m9.figshare.5104873.v1
专利: US09073871B2
来源说明: uspto-grants-2015_07

反应 SMILES

[C:1]1([C:7]2[CH:8]=[N:9][N:10]([C:12]3[N:17]=[CH:16][C:15]([NH:18][CH:19]([C:23]4[CH:33]=[CH:32][C:26]([C:27](OCC)=[O:28])=[CH:25][CH:24]=4)[CH2:20][CH2:21][CH3:22])=[CH:14][CH:13]=3)[CH:11]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:34][NH:35][CH2:36][CH2:37][C:38]([O:40][C:41]([CH3:44])([CH3:43])[CH3:42])=[O:39]>>[CH3:34][N:35]([CH2:36][CH2:37][C:38]([O:40][C:41]([CH3:44])([CH3:43])[CH3:42])=[O:39])[C:27](=[O:28])[C:26]1[CH:32]=[CH:33][C:23]([CH:19]([NH:18][C:15]2[CH:16]=[N:17][C:12]([N:10]3[CH:11]=[C:7]([C:1]4[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=4)[CH:8]=[N:9]3)=[CH:13][CH:14]=2)[CH2:20][CH2:21][CH3:22])=[CH:24][CH:25]=1