HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 42628942, compound → HCID 68445203, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 42628942 | HCID 42628942 | — |
| Reactant | 6-(5-Methyl-3-phenyl-isoxazol-4-ylmethoxy)-N-(tetrahydro-pyran-4-yl)-nicotinamide | HCID 57520014 | — |
| Product | HCID 68445203 | HCID 68445203 | 33% |
Reaction Steps
As described for example 50, N-isopropyl-6-(5-methyl-3-phenyl-isoxazol-4-ylmethoxy)-nicotinamide (200 mg, 0.6 mmol), instead of 6-(5-methyl-3-phenyl-isoxazol-4-ylmethoxy)-N-(tetrahydro-pyran-4-yl)-nicotinamide, was converted to the title compound (69 mg, 33%) which was obtained as a colourless gum. MS: m/e=366.3 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09073908B2 |
| Source dataset | uspto-grants-2015_07 |
| ORD ID | ord-82fef850437b48109941dc8c3df49306 |
| Source note | uspto-grants-2015_07 |