HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2R)-1-aminopropan-2-ol → (9S)-9-Methyl-6-oxo-6,7,8,9-tetrahydropyrido[3',2':4,5]pyrrolo[1,2-a]pyrazine-2-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2R)-1-aminopropan-2-ol | HCID 439938 | — |
| Reactant | (R)-9-methyl-6-oxo-6,7,8,9-tetrahydropyrido[3',2':4,5]pyrrolo[1,2-a]pyrazine-2-carboxylic acid | HCID 67236368 | — |
| Product | (9S)-9-Methyl-6-oxo-6,7,8,9-tetrahydropyrido[3',2':4,5]pyrrolo[1,2-a]pyrazine-2-carboxylic acid | HCID 67236747 | — |
Reaction Steps
(9S)-9-Methyl-6-oxo-6,7,8,9-tetrahydropyrido[3′,2′:4,5]pyrrolo[1,2-a]pyrazine-2-carboxylic acid is synthesized using the similar procedure used to prepare (9R)-9-methyl-6-oxo-6,7,8,9-tetrahydropyrido[3′,2′:4,5]pyrrolo[1,2-a]pyrazine-2-carboxylic acid (Intermediate J), replacing (S)-1-Aminopropan-2-ol with (R)-1-Aminopropan-2-ol in Step 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09073926B2 |
| Source dataset | uspto-grants-2015_07 |
| ORD ID | ord-be687b56759945428bebf3b138cd3c36 |
| Source note | uspto-grants-2015_07 |