HCID 67235215, compound → HCID 28373930, compound

Participants

Reaction Steps

A solution of 4-[(4-nitro-1H-pyrazol-1-yl)methyl]pyridine (247 mg, 1.21 mmol) in methanol (10 mL) is hydrogenated over 10% palladium on carbon (30 mg) under balloon pressure for 3 h. The mixture is filtered through Celite® and the filtrate is concentrated under reduced pressure. The residue is purified via flash column chromatography using a gradient elution of 0-10% CH2Cl2/methanol to afford the title compound as a brown oil (198 mg, 94%).

Provenance & Evidence