Acetate → HCID 66581119, compound

Participants

Reaction Conditions

Reaction Steps

Iodo benzene (0.15 mL, 1.15 mmol, 2 eq), palladium (Il) acetate (6.4 mg, 0.03 mmol, 0.05 eq), and Cul (0.22 g, 1.15 mmol, 2 eq) are taken in pressure tube to which is added ethyl 4H-imidazo[5,1-c][1,4]benzothiazine-3-carboxylate (0.15 g, 0.576 mmol, 1 eq) taken in degassed DMF (6 mL) and the contents are heated at 140° C. for 12 h. The reaction mixture is diluted with DCM and filtered through celite. The filtrate is concentrated, passed through a plug of silica gel and concentrated to get the crude product 60 mg which is taken as such to next step. MS (ESI+): 337.2.

Provenance & Evidence