HCID 71657494, compound → HCID 71657495, compound

HRID 1521892Notes

Reaction equation

[CH:1]([C:3]1[C:11]2[C:6](=[N:7][C:8]([C:19]3[CH:24]=[CH:23][C:22]([CH3:25])=[CH:21][CH:20]=3)=[C:9]([C:12]3[CH:17]=[CH:16][C:15]([CH3:18])=[CH:14][CH:13]=3)[N:10]=2)[N:5]([CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][C:32]([O:34]CC)=[O:33])[CH:4]=1)=[O:2].C1(C2N(CCCCCCC(O)=O)C3=NC(C4C=CC(C)=CC=4)=C(C4C=CC(C)=CC=4)N=C3C=2)CC1>>[CH:1]([C:3]1[C:11]2[C:6](=[N:7][C:8]([C:19]3[CH:24]=[CH:23][C:22]([CH3:25])=[CH:21][CH:20]=3)=[C:9]([C:12]3[CH:13]=[CH:14][C:15]([CH3:18])=[CH:16][CH:17]=3)[N:10]=2)[N:5]([CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][C:32]([OH:34])=[O:33])[CH:4]=1)=[O:2]

Participants

Reactant 2

HCID 71657494HCID 71657494, compound

HCID 86690313HCID 86690313, compound2×

Product 1

HCID 71657495HCID 71657495, compound

Procedure

The titled compound was prepared from ethyl 7-(7-formyl-2,3di-p-tolyl-5H-pyrrolo[2,3-b]pyrazin-5-yl)heptanoate (Intermediate C) analgously to 7-(6-cyclopropyl-2,3-di-p-tolyl-5H-pyrrolo[2,3-b]pyrazin-5-yl)heptanoic acid (Example 1 step 7);

Sources & evidence

ORD record: ord-8a8ba46058fd416f809218056ca54d4b
Source dataset: uspto-grants-2015_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09073932B2

Reaction notes

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