(S)-3-(3,4-dibenzyloxyphenoxy)-1,2-epoxypropane → HCID 86752189, compound

HRID 1522Notes

Reaction equation

HRID 1522 reaction equation
[CH2:1]([O:8][C:9]1[CH:10]=[C:11]([CH:17]=[CH:18][C:19]=1[O:20][CH2:21][C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1)[O:12][CH2:13][C@H:14]1[O:16][CH2:15]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:28][O:29][C:30](=[O:43])[CH2:31][O:32][C:33]1[CH:38]=[CH:37][C:36]([CH2:39][C@H:40]([NH2:42])[CH3:41])=[CH:35][CH:34]=1>>[CH2:1]([O:8][C:9]1[CH:10]=[C:11]([CH:17]=[CH:18][C:19]=1[O:20][CH2:21][C:22]1[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=1)[O:12][CH2:13][CH:14]([OH:16])[CH2:15][NH:42][CH:40]([CH3:41])[CH2:39][C:36]1[CH:37]=[CH:38][C:33]([O:32][CH2:31][C:30]([O:29][CH3:28])=[O:43])=[CH:34][CH:35]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 11689086(S)-3-(3,4-dibenzyloxyphenoxy)-1,2-epoxypropaneHCID 14372866HCID 14372866, compound

Product 1

HCID 86752189HCID 86752189, compound

Procedure

The title compound was prepared from (S)-3-(3,4-dibenzyloxyphenoxy)-1,2-epoxypropane and (R)-4-(2-aminopropyl)phenoxyacetic acid methyl ester according to the method described in Procedure 13.

Sources & evidence

ORD record
ord-86f5e49c8e57407dadc506848462b455
Source dataset
uspto-grants-1998_03
Patent number
US05726165

Reaction notes

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