Tetrabutylammonium Fluoride → HCID 90414185, compound

Participants

Reaction Steps

A solution of 1M tetrabutylammonium fluoride in tetrahydrofuran (3.1 mL, 3.10 mmol) was added to a solution of Example 260E (627 mg, 1.028 mmol) in tetrahydrofuran (5 mL) and the mixture was stirred at room temperature for 1 hour and concentrated. The residue was purified by flash chromatography on silica gel, eluting with a gradient of 0-7% methanol-dichloromethane to give the title compound. MS (ESI+) m/z 454.1 (M+H)+.

Provenance & Evidence