Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Phenoxyphenylboronic acid → HCID 71092988, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Phenoxyphenylboronic acid | HCID 2734377 | — |
| 반응물 | (2E)-4-(Dimethylamino)-2-butenoic acid | HCID 14805664 | — |
| 반응물 | 5,6-Dichloro-pyrimidin-4-ylamine | HCID 24219262 | — |
| 반응물 | Tert-butyl 3-(aminomethyl)-8-azabicyclo[3.2.1]octane-8-carboxylate | HCID 53487663 | — |
| 생성물 | HCID 71092988 | HCID 71092988 | — |
반응 단계
(E)-1-(3-(((6-amino-5-(4-phenoxyphenyl)pyrimidin-4-yl)amino)methyl)-8-azabicyclo[3.2.1]octan-8-yl)-4-(dimethylamino)but-2-en-1-one was prepared from 5,6-dichloropyrimidin-4-amine, tert-butyl 3-(aminomethyl)-8-azabicyclo[3.2.1]octane-8-carboxylate, (4-phenoxyphenyl)boronic acid, and (E)-4-(dimethylamino)but-2-enoic acid using methods B, C, D, and E. HPLC purity: 100%. MS: m/z=513 [M+H]+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09073947B2 |
| 출처 데이터셋 | uspto-grants-2015_07 |
| ORD ID | ord-4b7a2f624fab45d5b5a9038a5d85aba1 |
| 출처 메모 | uspto-grants-2015_07 |