HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → N-(3-(4-(4-phenoxyphenoxy)pyridin-3-yl)phenyl)propionamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Reactant | 3-(4-(4-Phenoxyphenoxy)pyridin-3-yl)aniline | HCID 71474010 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | N-(3-(4-(4-phenoxyphenoxy)pyridin-3-yl)phenyl)propionamide | HCID 71092779 | 65% |
Reaction Steps
N-(3-(4-(4-phenoxyphenoxy)pyridin-3-yl)phenyl)propionamide was prepared from 3-(4-(4-phenoxyphenoxy)pyridin-3-yl)aniline and pyridine instead of N,N-diethylethanamine, 1-methylpyrrolidin-2-one, dichloromethane using Method G (65% yield). HPLC: 92%, RT=4.234 min. MS: m/z=411 [M+H]+, RT=3.35 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09073947B2 |
| Source dataset | uspto-grants-2015_07 |
| ORD ID | ord-33862a5c9378408aa6e7b85b1ec71cee |
| Source note | uspto-grants-2015_07 |