Sodium Hydroxide → HCID 90116918, compound

HRID 1522321Notes

Reaction equation

HRID 1522321 reaction equation
[C:1]1([NH:7][C:8](=[O:14])/[CH:9]=[CH:10]\[C:11]([OH:13])=[O:12])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[OH-].[Na+:16]>>[Na+:16].[C:1]1([NH:7][C:8](=[O:14])/[CH:9]=[CH:10]\[C:11]([O-:13])=[O:12])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 1550938Maleic acid anilide

Product 1

HCID 90116918HCID 90116918, compound

Procedure

Aniline (1 mol) and maleic anhydride (1.0 mol) were subjected to an addition reaction at 20 to 30° C. for 2.5 hours to give N-phenylmaleamidic acid. Then, the resulting N-phenylmaleamidic acid was neutralized with sodium hydroxide under cooling to give an N-phenylmaleamidic acid sodium salt.

Workup

  1. temperatureunder cooling

Sources & evidence

ORD record
ord-73b3f93f41504e99879bf03278d77564
Source dataset
uspto-grants-2015_07
Patent number
US09074063B2

Reaction notes

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