Ethanolamine → HCID 57640009, compound

HRID 1522848Notes

Reaction equation

HRID 1522848 reaction equation
[CH3:1][C@@H:2]([CH2:7][C:8](OC)=O)[C:3](OC)=O.[NH2:12][CH2:13][CH2:14][OH:15]>>[CH3:1][C@H:2]1[CH2:7][CH2:8][N:12]([CH2:13][CH2:14][OH:15])[CH2:3]1

Participants

3

Reactant 2

HCID 700EthanolamineHCID 9964174HCID 9964174, compound

Product 1

HCID 57640009HCID 57640009, compound

Procedure

The title compound was synthesized as described in Intermediate 11 using (S)-dimethyl 2-methylsuccinate and 2-aminoethanol as starting materials. 1H NMR (CDCl3): δ 3.66 (t, 1H), 2.93 (dd, 1H), 2.81 (m, 1H), 2.73 (m, 1H), 2.66 (m, 1H), 2.63 (m, 1H), 2.29 (m, 1H), 2.18 (dd, 2H), 2.05 (m, 1H), 1.40 (m, 1H), 1.04 (d, 3H); MS: 130.2 (M+H)+.

Sources & evidence

ORD record
ord-f10ef9bf991f43eba7de2411e2426008
Source dataset
uspto-grants-2015_07
Patent number
US09078871B2

Reaction notes

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