Cyclohexanecarbohydrazide → HCID 178446190, compound

HRID 1522986Notes

Reaction equation

HRID 1522986 reaction equation
[CH2:1]([N:6]1[C:16]2[C:11](=[CH:12][CH:13]=[C:14]([O:17][CH3:18])[CH:15]=2)[C:9](=O)[C:7]1=[O:8])[CH2:2][CH2:3][CH2:4][CH3:5].[CH:19]1([C:25]([NH:27][NH2:28])=[O:26])[CH2:24][CH2:23][CH2:22][CH2:21][CH2:20]1>>[CH3:18][O:17][C:14]1[CH:15]=[C:16]2[C:11](/[C:9](=[N:28]/[NH:27][C:25]([CH:19]3[CH2:24][CH2:23][CH2:22][CH2:21][CH2:20]3)=[O:26])/[C:7](=[O:8])[N:6]2[CH2:1][CH2:2][CH2:3][CH2:4][CH3:5])=[CH:12][CH:13]=1

Participants

3

Reactant 2

HCID 240039CyclohexanecarbohydrazideHCID 251944561-Pentyl-6-methoxy-isatin

Product 1

HCID 178446190HCID 178446190, compound

Procedure

The title compound was prepared as a yellow solid, using 1-pentyl-6-methoxy-isatin obtained in Example 39(A) and cyclohexanecarbohydrazide according to the synthetic method E. NMR (CDCl3): δ 0.91 (t, 3H), 1.25 to 2.36 (m, 17H), 3.70 (t, 2H), 3.87 (s, 3H), 6.43 (d, 1H), 6.61 (dd, 1H), 7.51 and 7.73 (d for isomers, 1H), 12.28 and 13.078 (br s for isomers, 1H).

Sources & evidence

ORD record
ord-4f452c2bf4a448e4a5f59576c2474c76
Source dataset
uspto-grants-2015_07
Patent number
US09079854B2

Reaction notes

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