tert-Butyl carbazate → HCID 178446206, compound

HRID 1522988Notes

Reaction equation

HRID 1522988 reaction equation
[CH2:1]([N:6]1[C:16]2[C:11](=[CH:12][CH:13]=[C:14]([O:17][CH3:18])[CH:15]=2)[C:9](=O)[C:7]1=[O:8])[CH2:2][CH2:3][CH2:4][CH3:5].[C:19]([O:23][C:24]([CH3:27])([CH3:26])[CH3:25])(=[O:22])[NH:20][NH2:21]>>[CH3:18][O:17][C:14]1[CH:15]=[C:16]2[C:11](/[C:9](=[N:21]/[NH:20][C:19]([O:23][C:24]([CH3:27])([CH3:26])[CH3:25])=[O:22])/[C:7](=[O:8])[N:6]2[CH2:1][CH2:2][CH2:3][CH2:4][CH3:5])=[CH:12][CH:13]=1

Participants

3

Reactant 2

HCID 70091tert-Butyl carbazateHCID 251944561-Pentyl-6-methoxy-isatin

Product 1

HCID 178446206HCID 178446206, compound

Procedure

The title compound was prepared as a yellow solid, using 1-pentyl-6-methoxy-isatin obtained in Example 39(A) and tert-Butyl carbazate according to the synthetic method E. NMR (CDCl3): δ 0.91 (t, 3H), 1.36 to 1.39 (m, 4H), 1.54 9s, 9H), 1.69-1.75 (m, 2H), 3.70 (t, 2H), 3.86 (s, 3H), 6.41 (d, 1H), 6.60 (dd, 1H), 7.66 (d, 1H), 12.201 (br s, 1H).

Sources & evidence

ORD record
ord-c3af191a69d347ddb9e974380e1b2096
Source dataset
uspto-grants-2015_07
Patent number
US09079854B2

Reaction notes

Loading…