HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Chloro-3-iodobenzene → 1-tert-Butoxycarbonyl-4-[2-(3-chloro-phenylsulfanyl)-5-fluoro-phenyl]-piperidine-4-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Chloro-3-iodobenzene | HCID 12269 | — |
| Reactant | 4-(5-Fluoro-2-mercapto-phenyl)-4-hydroxy-piperidine-1-carboxylic acid tert-butyl ester | HCID 68682113 | — |
| Product | 1-tert-Butoxycarbonyl-4-[2-(3-chloro-phenylsulfanyl)-5-fluoro-phenyl]-piperidine-4-ol | HCID 68684587 | — |
Reaction Steps
Prepared from 4-hydroxy-4-(2-mercapto-5-fluoro-phenyl)-piperidine-1-carboxylic acid tert-butyl ester and 1-chloro-3-iodo-benzene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07732463B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-6a624a10c1a14545a7efd7318c2e227e |
| Source note | uspto-grants-2010_06 |