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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1523019Generated: October 25, 2026

1-Bromopropane → 5-Chloro-1-propylindoline-2,3-dione

https://huagongshe.com/reaction/1523019

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-BromopropaneHCID 7840—
Reactant5-chloro-1H-indole-2,3-dioneHCID 87203—
Reactant1-propyl-1H-indole-2,3-dioneHCID 1645090—
Product5-Chloro-1-propylindoline-2,3-dioneHCID 2988281—

Reaction Steps

Was prepared in an analogous manner to 1-propylindoline-2,3-dione using commercially available 5-chloroisatin (purchased from Fisher Scientific) and 1-bromo-propane (purchased from Fisher Scientific). 1H NMR δ 7.57 (m, 2H), 6.88 (d, 1H), 3.69 (t, 2H), 1.74 (m, 2H), 1.00 (t, 3H)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09079853B2
Source datasetuspto-grants-2015_07
ORD IDord-323984a0004545ef9894b63378841066
Source noteuspto-grants-2015_07