1-Bromopropane → Sbb038754

HRID 1523020Notes

Reaction equation

[CH2:1]([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[C:6](=[O:13])[C:5]1=[O:14])[CH2:2][CH3:3].[CH3:15]C1C=C2C(=CC=1)NC(=O)C2=O.BrCCC>>[CH3:15][C:9]1[CH:8]=[C:7]2[C:12](=[CH:11][CH:10]=1)[N:4]([CH2:1][CH2:2][CH3:3])[C:5](=[O:14])[C:6]2=[O:13]

Participants

Reactant 3

HCID 78401-Bromopropane

HCID 118405-Methylisatin

HCID 16450901-propyl-1H-indole-2,3-dione

Product 1

HCID 3125288Sbb038754

Procedure

Was prepared in an analogous manner to 1-propylindoline-2,3-dione using 5-methyl isatin (purchased from Fisher Scientific) and 1-bromo-propane (purchase from Fisher Scientific). 1H NMR δ 7.41 (m, 2H), 6.80 (d, 1H), 3.67 (t, 2H), 2.33 (s, 3H), 1.72 (m, 2H), 0.99 (t, 3H).

Sources & evidence

ORD record: ord-e65b00c1911c498ea3819f33d3284972
Source dataset: uspto-grants-2015_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09079853B2

Reaction notes

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