5-Chloro-1-isobutylindoline-2,3-dione → 5-Chloro-1-isobutyl-2-oxoindolin-3-yl benzoate

HRID 1523028Notes

Reaction equation

HRID 1523028 reaction equation
[C:1](OC1C2C(=CC=C(C)C=2)N(CC)C1=O)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Cl:23][C:24]1[CH:25]=[C:26]2[C:30](=[CH:31][CH:32]=1)[N:29]([CH2:33][CH:34]([CH3:36])[CH3:35])[C:28](=[O:37])[C:27]2=[O:38]>>[C:1]([O:38][CH:27]1[C:26]2[C:30](=[CH:31][CH:32]=[C:24]([Cl:23])[CH:25]=2)[N:29]([CH2:33][CH:34]([CH3:35])[CH3:36])[C:28]1=[O:37])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 47368655-Chloro-1-isobutylindoline-2,3-dioneHCID 904159121-Ethyl-5-methyl-2-oxoindolin-3-yl benzoate

Product 1

HCID 904183185-Chloro-1-isobutyl-2-oxoindolin-3-yl benzoate

Procedure

Was made in an analogous fashion to 1-ethyl-5-methyl-2-oxoindolin-3-yl benzoate using 5-chloro-1-isobutylindoline-2,3-dione. 1H NMR δ 8.11 (d, 2H), 7.60 (dd, 1H), 7.52-7.32 (m, 4H), 6.80 (d, 1H), 6.10 (s, 1H), 3.75 (m, 2H), 1.72-1.57 (m, 1H), 1.01 (dd, 6H).

Sources & evidence

ORD record
ord-4a1d7d1de4c642a8870e4c9036def33f
Source dataset
uspto-grants-2015_07
Patent number
US09079853B2

Reaction notes

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