5-Chloro-1-ethylindoline-2,3-dione → 5-Chloro-1-ethyl-2-oxoindolin-3-yl benzoate

HRID 1523030Notes

Reaction equation

HRID 1523030 reaction equation
[C:1]([O:9][CH:10]1[C:18]2[C:13](=[CH:14][CH:15]=[C:16](C)[CH:17]=2)[N:12]([CH2:20][CH3:21])[C:11]1=[O:22])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Cl:23]C1C=C2C(=CC=1)N(CC)C(=O)C2=O>>[C:1]([O:9][CH:10]1[C:18]2[C:13](=[CH:14][CH:15]=[C:16]([Cl:23])[CH:17]=2)[N:12]([CH2:20][CH3:21])[C:11]1=[O:22])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 29896025-Chloro-1-ethylindoline-2,3-dioneHCID 904159121-Ethyl-5-methyl-2-oxoindolin-3-yl benzoate

Product 1

HCID 904161685-Chloro-1-ethyl-2-oxoindolin-3-yl benzoate

Procedure

Was made in an analogous fashion to 1-ethyl-5-methyl-2-oxoindolin-3-yl benzoate using 5-chloro-1-ethylindoline-2,3-dione. 1H-NMR δ 8.11 (dd, 2H), 7.60 (dt, 1H), 7.47 (m, 2H) 7.45 (m, 1H), 7.33 (dd, 1H), 6.80 (d, 1H), 6.10 (d, 1H), 3.85 (m, 2H), 1.33 (t, 3H).

Sources & evidence

ORD record
ord-6fdf9c6ee9324aa499898fd7da08a5ac
Source dataset
uspto-grants-2015_07
Patent number
US09079853B2

Reaction notes

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