1-(2-methylpropyl)-2,3-dihydro-1H-indole-2,3-dione → 1-Isobutyl-2-oxoindolin-3-yl benzoate

HRID 1523036Notes

Reaction equation

HRID 1523036 reaction equation
[C:1](OC1C2C(=CC=C(C)C=2)N(CC)C1=O)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:23]([N:27]1[C:35]2[C:30](=[CH:31][CH:32]=[CH:33][CH:34]=2)[C:29](=[O:36])[C:28]1=[O:37])[CH:24]([CH3:26])[CH3:25]>>[C:1]([O:36][CH:29]1[C:30]2[C:35](=[CH:34][CH:33]=[CH:32][CH:31]=2)[N:27]([CH2:23][CH:24]([CH3:26])[CH3:25])[C:28]1=[O:37])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 23872331-(2-methylpropyl)-2,3-dihydro-1H-indole-2,3-dioneHCID 904159121-Ethyl-5-methyl-2-oxoindolin-3-yl benzoate

Product 1

HCID 904179011-Isobutyl-2-oxoindolin-3-yl benzoate

Procedure

Was made in an analogous fashion to 1-ethyl-5-methyl-2-oxoindolin-3-yl benzoate from 1-isobutylindoline-2,3-dione. 1H-NMR δ 8.10 (d, 2H), 7.59 (t, 1H), 7.46 (m, 3H), 7.34 (m, 1H), 7.05 (t, 1H), 6.89 (d, 1H), 6.18 (s, 1H), 3.52 (m, 2H), 2.18 (m, 1H), 1.01 (dd, 6H).

Sources & evidence

ORD record
ord-0a4316929e144c23aad6ff86e5ed55a9
Source dataset
uspto-grants-2015_07
Patent number
US09079853B2

Reaction notes

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