HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-chloro-1H-indole-2,3-dione → 5-Chloro-1-(3-morpholinopropyl)indoline-2,3-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-chloro-1H-indole-2,3-dione | HCID 87203 | — |
| Reactant | 1-propyl-1H-indole-2,3-dione | HCID 1645090 | — |
| Reactant | 4-(3-Bromopropyl)morpholine | HCID 13034048 | — |
| Product | 5-Chloro-1-(3-morpholinopropyl)indoline-2,3-dione | HCID 90417446 | — |
Reaction Steps
This compound was prepared in a similar method as 1-propylindoline-2,3-dione by reacting commercially available 5-chloro isatin (purchase from Fisher Scientific) with the 4-(3-bromopropyl)morpholine. 1H NMR δ 7.57 (m, 2H), 6.98 (d, 1H), 3.82 (t, 2H), 3.64 (m, 4H), 2.41 (m, 6H), 1.87 (m, 2H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09079853B2 |
| Source dataset | uspto-grants-2015_07 |
| ORD ID | ord-245acbc923f14820bdb9123a1209210e |
| Source note | uspto-grants-2015_07 |