反应详情

This compound was prepared in an analogous manner to 3-((3-bromopyridin-2-yl)methyl)-3-hydroxy-1-isopentyl-5-methylindolin-2-one using 5-chloro-1-(2-(piperidin-1-yl)ethyl)indoline-2,3-dione and 2-methylpyridine (purchased from Fisher Scientific). 1H-NMR δ 8.61 (d, 1H), 7.70 (m, 2H), 7.32 (dd, 1H), 7.24 (dd, 1H), 7.10 (d, 1H), 6.82 (m, 2H), 3.87-3.75 (m, 2H), 3.33 (d, 1H), 3.11 (d, 1H), 2.62-2.47 (m, 6H), 1.57 (m, 4H), 1.45 (m, 2H). Calculated mass for C21H24ClN3O2, 385.16, observed, 386.1 (M+1).