HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sbb038754 → 3-Hydroxy-3-((5-methoxypyridin-2-yl)methyl)-5-methyl-1-propylindolin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sbb038754 | HCID 3125288 | — |
| Reactant | 5-Methoxy-2-methylpyridine | HCID 13358777 | — |
| Reactant | 3-((3-Bromopyridin-2-yl)methyl)-3-hydroxy-1-isopentyl-5-methylindolin-2-one | HCID 90418661 | — |
| Product | 3-Hydroxy-3-((5-methoxypyridin-2-yl)methyl)-5-methyl-1-propylindolin-2-one | HCID 86300540 | — |
Reaction Steps
This compound was prepared in an analogous manner to 3-((3-bromopyridin-2-yl)methyl)-3-hydroxy-1-isopentyl-5-methylindolin-2-one using 5-methyl-1-propylindoline-2,3-dione and 5-methoxy-2-methylpyridine. 1H-NMR δ 8.3 (s, 1H), 7.20 (d, 1H), 7.08 (d, 1H), 6.98 (d, 1H), 6.73 (m, 2H), 4.2 (bs, OH), 3.92 (s, 3H), 3.61 (m, 2H), 3.23 (d, 1H), 3.12 (d, 1H), 2.62 (s, 3H), 1.70 (m, 2H), 0.97 (t, 3H). Calculated mass for C19H22N2O3, 326.16. Observed, 327.1 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09079853B2 |
| Source dataset | uspto-grants-2015_07 |
| ORD ID | ord-4e8b147777ba42129b8d23eb0ded6edb |
| Source note | uspto-grants-2015_07 |