5-Chloro-1-ethylindoline-2,3-dione → 5-Chloro-1-ethyl-3-hydroxy-3-((3-methoxypyridin-2-yl)methyl)indolin-2-one

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Reaction Steps

This compound was prepared in an analogous manner to 3-((3-bromopyridin-2-yl)methyl)-3-hydroxy-1-isopentyl-5-methylindolin-2-one using 5-chloro-1-ethylindoline-2,3-dione and 3-methoxy-2-methylpyridine. 1H-NMR δ 8.21 (s, 1H), 7.5 (bs, OH), 7.26 (m, 3H), 6.99 (s, 1H), 6.78 (d, 1H), 3.77 (s, 3H), 3.76 (m, 2H), 3.45 (d, 1H), 3.19 (d, 1H), 1.27 (t, 3H). Calculated mass for C17H17ClN2O3, 332.09. Observed, 333.1 (M+1).

Provenance & Evidence