反应详情

This compound was prepared in an analogous manner to 3-((3-bromopyridin-2-yl)methyl)-3-hydroxy-1-isopentyl-5-methylindolin-2-one using 5-methyl-1-phenethylindoline-2,3-dione and 5-methoxy-2-methylpyridine (purchased from Aldrich). 1H-NMR δ 8.29 (d, 1H), 7.34 (m, 2H), 7.25 (m, 3H), 7.18 (dd, 1H), 7.07 (dd, 1H), 6.90 (d, 1H), 6.80 (s, 1H), 6.71 (d, 1H), 5.3 (bs, OH), 3.98 (dt, 1H), 3.91 (s, 3H), 3.81 (dt, 1H), 3.05 (d, 2H), 2.97 (t, 2H), 2.27 (s, 3H). Calculated mass for C24H24N2O3, 388.18. Observed 389.2 (M+1).