HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Acetylindole → 3-(2-(1H-indol-3-yl)-2-oxoethyl)-3-hydroxy-1-isopentylindolin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Acetylindole | HCID 12802 | — |
| Reactant | 1-(3-methylbutyl)-1H-indole-2,3-dione | HCID 2362593 | — |
| Reactant | 1-Butyl-3-hydroxy-3-(2-oxo-2-pyridin-2-ylethyl)indol-2-one | HCID 2944160 | — |
| Product | 3-(2-(1H-indol-3-yl)-2-oxoethyl)-3-hydroxy-1-isopentylindolin-2-one | HCID 86300241 | — |
Reaction Steps
This compound was made in a similar manner to 1-butyl-3-hydroxy-3-(2-oxo-2-(pyridin-2-yl)ethyl)indolin-2-one using 1-isopentylindoline-2,3-dione and commercially available 1-(1H-indol-3-yl)ethanone (purchased from Fisher Scientific). 1H-NMR δ 9.41 (bs, 1H), 8.33 (s, 1H), 7.82 (m, 1H), 7.66 (d, 1H), 7.47 (d, 1H), 7.25 (m, 3H), 7.00 (t, 1H), 6.84 (d, 1H), 5.89 (bs, 1H), 3.71 (t, 2H), 3.49 (d, 1H), 3.21 (d, 1H), 1.62 (m, 2H), 1.54 (m, 1H), 0.94 (dd, 6H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09079853B2 |
| Source dataset | uspto-grants-2015_07 |
| ORD ID | ord-205d913f4fa54ddb85f990247197774a |
| Source note | uspto-grants-2015_07 |