HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Butyl-3-hydroxy-3-(2-oxo-2-pyridin-2-ylethyl)indol-2-one → 3-(2-(2,6-Dimethoxypyridin-3-yl)-2-oxoethyl)-3-hydroxy-5-methyl-1-propylindolin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Butyl-3-hydroxy-3-(2-oxo-2-pyridin-2-ylethyl)indol-2-one | HCID 2944160 | — |
| Reactant | Sbb038754 | HCID 3125288 | — |
| Reactant | 3-Acetyl-2,6-dimethoxypyridine | HCID 16218074 | — |
| Product | 3-(2-(2,6-Dimethoxypyridin-3-yl)-2-oxoethyl)-3-hydroxy-5-methyl-1-propylindolin-2-one | HCID 86300685 | — |
Reaction Steps
This compound was made in a similar manner to 1-butyl-3-hydroxy-3-(2-oxo-2-(pyridin-2-yl)ethyl)indolin-2-one using 5-methyl-1-propylindoline-2,3-dione and 1-(2,6-dimethoxypyridin-3-yl)ethanone (purchased from Fisher Scientific). 1H-NMR δ 8.14 (d, 1H) 7.23 (s, 1H), 7.08 (d, 1H), 6.76 (d, 1H), 6.36 (d, 1H), 4.67 (s, 1H), 3.99 (d, 6H), 3.69 (d, 1H), 3.66 (m, 2H), 3.47 (d, 1H), 2.29 (s, 3H), 1.75 (m, 2H), 0.98 (t, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09079853B2 |
| Source dataset | uspto-grants-2015_07 |
| ORD ID | ord-1e01dcd94ab54d24bf8554bfc4a18315 |
| Source note | uspto-grants-2015_07 |