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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1523073Generated: October 30, 2026

1-(6-Methoxypyridin-2-yl)ethan-1-one → 1-(3-Azidopropyl)-3-hydroxy-3-(2-(6-methoxypyridin-2-yl)-2-oxoethyl)-5-methylindolin-2-one

https://huagongshe.com/reaction/1523073

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(6-Methoxypyridin-2-yl)ethan-1-oneHCID 13642086—
Reactant1-(3-Azidopropyl)-5-methylindoline-2,3-dioneHCID 71540789—
Reactant3-(2-(1H-indol-3-yl)-2-oxoethyl)-1-(3-azidopropyl)-3-hydroxy-5-methylindolin-2-oneHCID 86300828—
Product1-(3-Azidopropyl)-3-hydroxy-3-(2-(6-methoxypyridin-2-yl)-2-oxoethyl)-5-methylindolin-2-oneHCID 86300683—

Reaction Steps

This compound was made in a similar manner to 3-(2-(1H-indol-3-yl)-2-oxoethyl)-1-(3-azidopropyl)-3-hydroxy-5-methylindolin-2-one using 1-(3-azidopropyl)-5-methylindoline-2,3-dione and 1-(6-methoxypyridin-2-yl)ethanone (commercially available from Fisher Scientific).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09079853B2
Source datasetuspto-grants-2015_07
ORD IDord-f713b2517cf54bdbb889600e6d92dad0
Source noteuspto-grants-2015_07