HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Butyl-3-hydroxy-3-(2-oxo-2-pyridin-2-ylethyl)indol-2-one → 5,7-Dichloro-3-hydroxy-3-(2-(6-methoxypyridin-2-yl)-2-oxoethyl)-1-propylindolin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Butyl-3-hydroxy-3-(2-oxo-2-pyridin-2-ylethyl)indol-2-one | HCID 2944160 | — |
| Reactant | 1-Isobutyl-5-methylindoline-2,3-dione | HCID 4730240 | — |
| Reactant | 5,7-Dichloro-1-propylindoline-2,3-dione | HCID 18803782 | — |
| Product | 5,7-Dichloro-3-hydroxy-3-(2-(6-methoxypyridin-2-yl)-2-oxoethyl)-1-propylindolin-2-one | HCID 86300682 | — |
Reaction Steps
This compound was made in a similar manner to 1-butyl-3-hydroxy-3-(2-oxo-2-(pyridin-2-yl)ethyl)indolin-2-one using 5,7-dichloro-1-propylindoline-2,3-dione and 1-isobutyl-5-methylindoline-2,3-dione (purchased from Fisher Scientific). 1H-NMR δ 7.74 (dd, 1H), 7.65 (dd, 1H), 7.37-7.25 (m, 2H), 6.99 (dd, 1H), 5.31 (bs, OH), 4.04-3.96 (m, 6H), 3.53 (dd, 1H), 1.77 (m, 2H), 0.92 (t, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09079853B2 |
| Source dataset | uspto-grants-2015_07 |
| ORD ID | ord-f9fe3835f7704fa984539d29c4a01757 |
| Source note | uspto-grants-2015_07 |