HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Ethyl-3-hydroxy-5-methyl-3-(3,4,5-trimethoxybenzyl)indolin-2-one → 3-Hydroxy-1-isobutyl-5-methyl-3-(3,4,5-trimethoxybenzyl)indolin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Ethyl-3-hydroxy-5-methyl-3-(3,4,5-trimethoxybenzyl)indolin-2-one | HCID 86300542 | — |
| Reactant | 1-Isobutyl-5-methyl-2-oxoindolin-3-yl benzoate | HCID 90416087 | — |
| Product | 3-Hydroxy-1-isobutyl-5-methyl-3-(3,4,5-trimethoxybenzyl)indolin-2-one | HCID 86301125 | — |
Reaction Steps
This compound was made in an analogous fashion to 1-ethyl-3-hydroxy-5-methyl-3-(3,4,5-trimethoxybenzyl)indolin-2-one using 5-methyl-1-isobutyl-2-oxoindolin-3-yl benzoate. 1H-NMR δ 7.22 (s, 1H), 7.08 (d, 1H), 6.58 (d, 2H), 6.1 (s, 2H), 3.74 (s, 3H), 3.63 (s, 6H), 3.48 (m, 1H), 3.29 (d, 1H), 3.11 (m, 1H), 3.06 (bs, OH), 2.35 (s, 3H), 1.85 (m, 1H), 0.70 (dd, 6H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09079853B2 |
| Source dataset | uspto-grants-2015_07 |
| ORD ID | ord-f294a3115a704ab8ad10b8c400aa1fce |
| Source note | uspto-grants-2015_07 |