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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1523089Generated: October 30, 2026

3,4-Dimethoxybenzyl bromide → 3-(3,4-Dimethoxybenzyl)-1-isopentyl-5-methyl-2-oxoindolin-3-yl benzoate

https://huagongshe.com/reaction/1523089

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,4-Dimethoxybenzyl bromideHCID 10900458—
Reactant1-Ethyl-5-methyl-2-oxo-3-(3,4,5-trimethoxybenzyl)indolin-3-yl benzoateHCID 86300681—
Reactant1-Isopentyl-5-methyl-2-oxoindolin-3-yl benzoateHCID 90414979—
Product3-(3,4-Dimethoxybenzyl)-1-isopentyl-5-methyl-2-oxoindolin-3-yl benzoateHCID 90418326—

Reaction Steps

This compound was made in an analogous fashion to 1-ethyl-5-methyl-2-oxo-3-(3,4,5-trimethoxybenzyl)indolin-3-yl benzoate using 1-isopentyl-5-methyl-2-oxoindolin-3-yl benzoate and 4-(bromomethyl)-1,2-dimethoxybenzene. 1H-NMR δ 8.06 (d, 2H), 7.57 (t, 1H), 7.43 (t, 2H), 7.08 (d, 1H), 6.93 (s, 1H), 6.67 (d, 1H), 6.60 (t, 2H), 6.36 (s, 1H), 3.82 (s, 3H), 3.64 (m, 4H), 3.46 (m, 2H), 3.26 (d, 1H), 2.27 (s, 3H), 1.50 (m, 1H), 1.26 (m, 2H) 0.92 (dd, 6H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09079853B2
Source datasetuspto-grants-2015_07
ORD IDord-5109fafe4d124acfb484256ed4adc51d
Source noteuspto-grants-2015_07