1-Ethyl-5-methyl-2-oxo-3-(3,4,5-trimethoxybenzyl)indolin-3-yl benzoate → 5-Chloro-2-oxo-1-phenethyl-3-(3,4,5-trimethoxybenzyl)indolin-3-yl benzoate

HRID 1523092Notes

Reaction equation

HRID 1523092 reaction equation
C(OC1([CH2:23][C:24]2[CH:29]=[C:28]([O:30][CH3:31])[C:27]([O:32][CH3:33])=[C:26]([O:34][CH3:35])[CH:25]=2)C2C(=CC=C(C)C=2)N(CC)C1=O)(=O)C1C=CC=CC=1.[C:36]([O:44][CH:45]1[C:53]2[C:48](=[CH:49][CH:50]=[C:51]([Cl:54])[CH:52]=2)[N:47]([CH2:55][CH2:56][C:57]2[CH:62]=[CH:61][CH:60]=[CH:59][CH:58]=2)[C:46]1=[O:63])(=[O:43])[C:37]1[CH:42]=[CH:41][CH:40]=[CH:39][CH:38]=1>>[C:36]([O:44][C:45]1([CH2:23][C:24]2[CH:25]=[C:26]([O:34][CH3:35])[C:27]([O:32][CH3:33])=[C:28]([O:30][CH3:31])[CH:29]=2)[C:53]2[C:48](=[CH:49][CH:50]=[C:51]([Cl:54])[CH:52]=2)[N:47]([CH2:55][CH2:56][C:57]2[CH:58]=[CH:59][CH:60]=[CH:61][CH:62]=2)[C:46]1=[O:63])(=[O:43])[C:37]1[CH:42]=[CH:41][CH:40]=[CH:39][CH:38]=1

Participants

3

Reactant 2

HCID 863006811-Ethyl-5-methyl-2-oxo-3-(3,4,5-trimethoxybenzyl)indolin-3-yl benzoateHCID 904162385-Chloro-2-oxo-1-phenethylindolin-3-yl benzoate

Product 1

HCID 904183825-Chloro-2-oxo-1-phenethyl-3-(3,4,5-trimethoxybenzyl)indolin-3-yl benzoate

Procedure

This compound was made in an analogous fashion to 1-ethyl-5-methyl-2-oxo-3-(3,4,5-trimethoxybenzyl)indolin-3-yl benzoate using 5-chloro-2-oxo-1-phenethylindolin-3-yl benzoate.

Sources & evidence

ORD record
ord-54d8021978864bf792b4b81420f72111
Source dataset
uspto-grants-2015_07
Patent number
US09079853B2

Reaction notes

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