(2-Bromo-imidazo[2,1-b]thiazol-6-yl)-carbamic acid tert-butyl ester → tert-butyl N-[2-[4-[2-[1-[2-(methoxycarbonylamino)-3-methylbutanoyl]pyrrolidin-2-yl]-1H-imidazol-5-yl]phenyl]imidazo[2,1-b][1,3]thiazol-6-yl]carbamate
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][c:8]1[n:9][c:10]2[s:11][c:12]([Br:16])[cH:13][n:14]2[cH:15]1)=[O:17].[CH3:18][O:19][C:20]([NH:21][CH:22]([CH:23]([CH3:24])[CH3:25])[C:26](=[O:27])[N:28]1[CH:29]([c:33]2[nH:34][c:35](-[c:38]3[cH:39][cH:40][c:41]([B:44]4[O:45][C:46]([CH3:47])([CH3:48])[C:49]([CH3:50])([CH3:51])[O:52]4)[cH:42][cH:43]3)[cH:36][n:37]2)[CH2:30][CH2:31][CH2:32]1)=[O:53]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][c:8]1[n:9][c:10]2[s:11][c:12](-[c:41]3[cH:40][cH:39][c:38](-[c:35]4[nH:34][c:33]([CH:29]5[N:28]([C:26]([CH:22]([NH:21][C:20]([O:19][CH3:18])=[O:53])[CH:23]([CH3:24])[CH3:25])=[O:27])[CH2:32][CH2:31][CH2:30]5)[n:37][cH:36]4)[cH:43][cH:42]3)[cH:13][n:14]2[cH:15]1)=[O:17]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-01fe953580f14476b2d6d6edde30abe0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
Loading…