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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 152343Generated: October 26, 2026

Tetrahydrofuran → 2-(3,5-Dichloropyridin-4-yl)-1-{9-methoxy-spiro[2H-1,5-benzodioxepin-3(4H),3'-oxetane]-6-yl}ethanone

https://huagongshe.com/reaction/152343

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantLithium ionHCID 28486—
ReactantNpc316347HCID 3280088—
Reactant3,5-Dichloro-4-methylpyridineHCID 10953827—
Reactant9-Methoxy-spiro[2H-1,5-benzodioxepin-3(4H),3'-oxetane]-6-carboxylic acid methyl esterHCID 59286710—
Product2-(3,5-Dichloropyridin-4-yl)-1-{9-methoxy-spiro[2H-1,5-benzodioxepin-3(4H),3'-oxetane]-6-yl}ethanoneHCID 25005168—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-703f589028654c5da4f4fe83d3439ca0
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)