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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1523552Generated: November 1, 2026

2-(4-(benzyloxy)-1H-pyrazol-1-yl)ethanol → HCID 67486723, compound

https://huagongshe.com/reaction/1523552

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(4-(benzyloxy)-1H-pyrazol-1-yl)ethanolHCID 67486330—
ReactantHCID 178418361HCID 178418361—
CatalystPalladiumHCID 23938—
SolventTetrahydrofuranHCID 8028—
ProductHCID 67486723HCID 67486723169.3%

Reaction Steps

2-(4-(benzyloxy)-1H-pyrazol-1-yl)ethanol (1.81 g, 8.3 mmol) was dissolved in THF (15 mL) under nitrogen. Pd/C (0.22 g, 0.21 mmol) was added and the solution was placed under vacuum and charged with a hydrogen balloon. The mixture stirred at ambient temperature overnight under this hydrogen atmosphere. The solution was filtered through GF/F paper and concentrated to give 1-(2-hydroxyethyl)-1H-pyrazol-4-ol (1.8 g, quantitative).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09079890B2
Source datasetuspto-grants-2015_07
ORD IDord-5934fb888f204929a56bc82c6fa7f901
Source noteuspto-grants-2015_07