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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1523829Generated: November 4, 2026

2-Bromoaniline → HCID 90314330, compound

https://huagongshe.com/reaction/1523829

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-BromoanilineHCID 11992—
Reactant5-(2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-phenyl)-pyrazin-2-amineHCID 90312276—
ProductHCID 90314330HCID 90314330—

Reaction Steps

The title compound was prepared using analogous conditions to those described in Example 6 utilizing 5-(2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-pyrazin-2-amine and 2-bromoaniline. MS (ESI): mass calcd. for C16H13FN4, 280.11; m/z found, 281.1 [M+H]+. 1H NMR (400 MHz, DMSO-d6) δ 8.36 (s, 1H), 8.02 (s, 1H), 7.91 (m, 1H), 7.31 (d, J=12.7, 2H), 7.04 (d, J=7.3, 2H), 6.82-6.58 (m, 4H), 4.94 (s, 2H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09079866B2
Source datasetuspto-grants-2015_07
ORD IDord-5f191a9dccf140bb87efdbb38bb4e957
Source noteuspto-grants-2015_07