HuagongsheHuagongshe Chemistry Print Report · For research reference only
(4-Chloro-2-fluorophenyl)boronic acid → 7-(4-Chloro-2-fluorophenyl)-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (4-Chloro-2-fluorophenyl)boronic acid | HCID 4193595 | — |
| Reactant | 7-Bromo-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine | HCID 24229635 | — |
| Product | 7-(4-Chloro-2-fluorophenyl)-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine | HCID 90312868 | — |
Reaction Steps
Prepared in a manner similar to that found in Example 1 using of 7-bromo-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine with (4-chloro-2-fluorophenyl)boronic acid. 1H NMR (400 MHz, CDCl3) δ 7.84 (m, 1H), 7.35-7.28 (m, 1H), 7.20-7.14 (m, 3H), 4.29-4.25 (m, 2H), 3.64-3.58 (m, 2H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09079866B2 |
| Source dataset | uspto-grants-2015_07 |
| ORD ID | ord-68a452c0644f4ab7aaf70da2e63c0172 |
| Source note | uspto-grants-2015_07 |