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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1523956생성일: 2026년 10월 27일

5-bromo-1H-pyrrolo(2,3-b)pyridine-3-carbaldehyde → 3'-fluoro-4'-(3-formyl-1H-pyrrolo[2,3-b]pyridin-5-yl)-N-methyl-[1,1'-biphenyl]-2-sulfonamide

https://huagongshe.com/reaction/1523956

반응식

참여 물질

역할이름HCID투입량
반응물5-bromo-1H-pyrrolo(2,3-b)pyridine-3-carbaldehydeHCID 24729605—
반응물3'-Fluoro-N-methyl-4'-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-[1,1'-biphenyl]-2-sulfonamideHCID 90313202—
생성물3'-fluoro-4'-(3-formyl-1H-pyrrolo[2,3-b]pyridin-5-yl)-N-methyl-[1,1'-biphenyl]-2-sulfonamideHCID 90312885—

반응 단계

The title compound was prepared using analogous conditions to those described in Example 88 using 5-bromo-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde and 3′-fluoro-N-methyl-4′-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-[1,1′-biphenyl]-2-sulfonamide. MS (ESI): mass calcd. for C21H16FN3O3S, 409.09; m/z found, 410.2 [M+H]+.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US09079866B2
출처 데이터셋uspto-grants-2015_07
ORD IDord-e26e5688b5fc4389a81ce2291d7889d8
출처 메모uspto-grants-2015_07