HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-bromo-1H-pyrrolo(2,3-b)pyridine-3-carbaldehyde → N-(tert-butyl)-3'-fluoro-4'-(3-formyl-1H-pyrrolo[2,3-b]pyridin-5-yl)-[1,1'-biphenyl]-2-sulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-bromo-1H-pyrrolo(2,3-b)pyridine-3-carbaldehyde | HCID 24729605 | — |
| Reactant | N-(tert-butyl)-3'-fluoro-4'-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-[1,1'-biphenyl]-2-sulfonamide | HCID 90313401 | — |
| Product | N-(tert-butyl)-3'-fluoro-4'-(3-formyl-1H-pyrrolo[2,3-b]pyridin-5-yl)-[1,1'-biphenyl]-2-sulfonamide | HCID 90314886 | — |
Reaction Steps
The title compound was prepared using analogous conditions to those described in Example 88 using 5-bromo-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde and N-(tert-butyl)-3′-fluoro-4′-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-[1,1′-biphenyl]-2-sulfonamide. MS (ESI): mass calcd. for C24H22FN3O3S, 451.14; m/z found, 452.2 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09079866B2 |
| Source dataset | uspto-grants-2015_07 |
| ORD ID | ord-c7ce3e0aab00441284b753278874c3a3 |
| Source note | uspto-grants-2015_07 |