HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Bromo-2-(trifluoromethoxy)benzene → HCID 90314157, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Bromo-2-(trifluoromethoxy)benzene | HCID 2777266 | — |
| Reactant | 5-(2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-phenyl)-pyrazin-2-amine | HCID 90312276 | — |
| Product | HCID 90314157 | HCID 90314157 | — |
Reaction Steps
The title compound was prepared using analogous conditions to those described in Example 1 utilizing 5-(2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)pyrazin-2-amine and 2-(trifluoromethoxy)bromobenzene. MS (ESI): mass calcd. for C17H11F4N3O, 349.08; m/z found, 350.0 [M+H]+. 1H NMR (400 MHz, DMSO-d6) δ 8.39 (s, 1H), 8.02 (s, 1H), 7.96 (m, 1H), 7.65-7.47 (m, 4H), 7.42 (d, J=5.1, 1H), 7.39 (s, 1H), 6.73 (s, 2H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09079866B2 |
| Source dataset | uspto-grants-2015_07 |
| ORD ID | ord-42f800fdfe1449ffb75049f6227b114d |
| Source note | uspto-grants-2015_07 |