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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1524032Generated: November 3, 2026

HCID 62958718, compound → HCID 90314822, compound

https://huagongshe.com/reaction/1524032

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 62958718HCID 62958718—
Reactant5-(2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)pyrimidin-2-amineHCID 90313142—
ProductHCID 90314822HCID 90314822—

Reaction Steps

The title compound was prepared in a manner similar to that described in Example 88 using 2-(2-bromophenoxy)-4-methylpyrimidine and 5-(2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)pyrimidin-2-amine. MS (ESI): mass calcd. for C21H16FN5O, 373.13; m/z found, 374.1 [M+H]+. 1H NMR (500 MHz, DMSO-d6) δ 8.44 (s, 2H), 8.39 (d, J=5.1, 1H), 7.57-7.44 (m, 3H), 7.41-7.31 (m, 3H), 7.25 (d, J=7.2, 1H), 7.07 (d, J=4.9, 1H), 6.89 (s, 2H), 2.35 (s, 3H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09079866B2
Source datasetuspto-grants-2015_07
ORD IDord-9a4d3bab0d5b43769910649d0c9b165b
Source noteuspto-grants-2015_07