HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 62958718, compound → HCID 90314822, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 62958718 | HCID 62958718 | — |
| Reactant | 5-(2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)pyrimidin-2-amine | HCID 90313142 | — |
| Product | HCID 90314822 | HCID 90314822 | — |
Reaction Steps
The title compound was prepared in a manner similar to that described in Example 88 using 2-(2-bromophenoxy)-4-methylpyrimidine and 5-(2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)pyrimidin-2-amine. MS (ESI): mass calcd. for C21H16FN5O, 373.13; m/z found, 374.1 [M+H]+. 1H NMR (500 MHz, DMSO-d6) δ 8.44 (s, 2H), 8.39 (d, J=5.1, 1H), 7.57-7.44 (m, 3H), 7.41-7.31 (m, 3H), 7.25 (d, J=7.2, 1H), 7.07 (d, J=4.9, 1H), 6.89 (s, 2H), 2.35 (s, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09079866B2 |
| Source dataset | uspto-grants-2015_07 |
| ORD ID | ord-9a4d3bab0d5b43769910649d0c9b165b |
| Source note | uspto-grants-2015_07 |